Friday, August 04, 2006

Increasing Orgasm in Women

Increasing Orgasm in Women

Nitric oxide increases the incidence of orgasm in women because nitric oxide allows clitoral and vaginal tissues to enlarge and become responsive. Nitric oxide levels can easily be increased in women by taking an amino acid called L-arginine.

Increasing Orgasm in Women

Nitric oxide increases the incidence of orgasm in women because nitric oxide allows clitoral and vaginal tissues to enlarge and become responsive. Nitric oxide levels can easily be increased in women by taking an amino acid called L-arginine.

Another way to insure orgasms in women is to increase niacin levels in the uterus, The Masters and Johnson study found that women cannot achieve orgasm without having sufficient levels of niacin in the uterine walls. Niacin can be purchased at any health food store or vitamin company, and is commonly found in B-complex formulas. High-dosing is not recommended for beginners, as flushing can occur. Certain types and levels of niacin will cause "flushing." Flushing is a common positive side effect of the vasodialation caused by niacin. Vasodialation is beneficial but has the potential harmless side effect of causing the ears to turn bright red and the skin to itch madly. Pharmacists frequently receive frantic calls from people who have taken an excess dose of niacin and fear they are experiencing a heart attack or severe allergic reaction.

Those electing to take niacin may wish to start with smaller doses (5-10 mg) taken with food and work up to higher doses as recommended by their health care professional. Niacinamide is commonly recommended as a replacement to niacin, but niacinamide does not have the beneficial effects that niacin does and niacinamide does not replace niacin in the uterine wall. Both niacin and vitamin E are beneficial vitamins for women who want to re-spark sexual interest and response.

The appropriate form of vitamin E (which is the dry, natural form) can be found in health food stores. Liquid vitamin E gel caps are not recommended due to their ability to oxidize. Ask for natural dry vitamin E in capsule, not tablet form. Do not be dissuade by energetic salespersons claiming that all vitamin E is the same. It is not. Natural dry powdered vitamin E is vastly superior, though a bit more expensive. The recommended dosage is 400 IU with breakfast and 400 IU with the last meal or snack of the day, for a total of 800 IU per day. Do not take more than 800 IU per day without a doctor’s permission.

Nitric Oxide Mechanism

There is a natural, non-drug method of creating nitric oxide in the human body. The mechanism is complex, but the trigger-mechanism is not. To produce nitric oxide in the body, a terminal nitrogen atom must combine with an oxygen molecule in the blood. An enzyme called nitric oxide synthase controls this reaction and NADPH, a niacin-containing redox-active electron storage compound, mediates the reaction.

This reaction can be accomplished via oral ingestion of formulas that contain the free form amino acid L-arginine. To put it simply, L-arginine equals nitric oxide. The left-handed molecule, L-arginine, is the primary source for NO in humans. NO produced in the body by L-arginine is called ADNO, or Arginine-Derived-Nitric-Oxide. An added benefit of taking L-arginine is improvement in immune function and reduced wound-healing time (1). Since the precursor to the neurotransmitter nitric oxide is L-arginine, a formula containing L-arginine can be effective as an alternative to Viagra, but the formula must be carefully designed not to increase or stimulate the production of free radicals and/or peroxynitrite. Do not rush out and buy plain L-arginine, because L-arginine without the correct synergists and co-factors or an improperly prepared L-arginine formula can cause reactivation of the herpes virus as well as the stimulation of peroxynitrate. Formulas containing free forms of both L-arginine and Lysine are to be avoided.

Non-Drug Nitric Oxide Formulas

Non-drug Nutraceutical formulations can be designed to target enhanced sexual function by producing NO in the human body. It is essential, in the formulation of a nitric oxide precursor, that the safe pathway for accessing NO is followed meticulously. Excessive production of NO and activation of NO via incorrect pathways (using un-orthodox Viagra alternatives) can cause brain-related free radical damage. Production of nitric acid through the combination of immune and nervous system activity plays a key role in the development of neurological diseases (2). This brings into question the possible damage to the body caused by using drugs that stimulate the production of NO through non-natural, non-L-arginine means.

NO can be introduced naturally into the body, but the key is to do so without sparking peroxynitrite, a biologically essential oxidant that is the most toxic free radical to the body. The natural methodology for stimulating NO should be safe and without side effects. Certain new Viagra-like products use herbal preparations and other methodologies to effect an increase in NO. Caution should be used in the selection of these new products and it should be ascertained that the product does not cause an increase in, or stimulate the production of free radicals and/or peroxynitrite.

Clinical Benefits of L-Arginine
L-arginine, taken orally, is a natural, non-drug alternative that safely increases nitric oxide in the body. Aside from the nitric oxide benefits attributed to L-arginine, the additional health benefits are nothing short of astounding. The clinician and researcher will appreciate the myriad of well executed studies that have been done which verity L-arginine's efficacy as an anti-aging agent.

Clinically Proven Benefits of L-Arginine

7 grams of L-arginine per day improved blood flow in men, aged 55 to 77, with elevated serum cholesterol and early coronary artery disease. Circulation

L-arginine supplementation reduced pathological increases in the thickness of plaque-lined vessel walls in people with elevated cholesterol and artherosclerosis. Circulation

Arginine lowered plasma cholesterol levels in patients with advanced hypertension.
New England Journal of Medicine

Arginine infusion has the same effect in cardiovascular patients as cholesterol-lowering drugs. The Lancet

17 grams of L-arginine per day given orally to elderly patients for 2 weeks resulted in a significant improvement in their lipid profile, with no adverse side effects.
Journal of Perenteral & Enteral Nutrition

8.4 grams L-arginine given 3 times a day significantly enhanced coronary artery blood flow in heart patients. Journal of the American College of Cardiology

7 grams of L-arginine improved blood-vessel relaxation in young men with elevated serum cholesterol and coronary artery disease (in as few as 3 days). Circulation

L-Arginine Dosage

The benefits of L-arginine supplementation are clearly dose-dependent. Beneficial dosages of L-arginine (per clinical studies) range from between 3 to 30 grams taken orally per day.

Dosages for Nitric Oxide:

Adequate dosages of L-arginine required for ADNO (nitric oxide) are 3 to 6 grams per day divided into three equal doses. Example: 2 g mid-morning, 2 g mid-afternoon, 2 g evening.

Dosages for Athletes:

Stimulation of growth hormone via oral administration of L-arginine requires higher doses taken at bedtime on a totally empty stomach:

Males 9 g to 21 g
(depending on body weight)

Females 6 g to 18 g (depending on body weight)

World-class athletes and professional bodybuilders take 10-15 grams of L-arginine at bedtime in a low glycemic base with appropriate cofactors (a). They report that their erections are frequently so strong upon arising; they are required to bend over to urinate. Further description would be indelicate. Though the benefits are pleasant, athletes do not take L-arginine to increase sexual function. They use L-arginine to naturally increase growth hormone levels, reduce injury, increase muscle mass, and to replace steroids. The average person is not required or recommended to use the same high doses of L-arginine as professional athletes.

Finding the Right L-Arginine/NO Product

When shopping for an L-arginine nitric oxide formula, make sure the research behind the formula is valid and safe (at least ten years of research). If the company marketing an L-arginine formula cannot validate that they have had an L-arginine product publicly "on the marker” for at least five years with no FDA/FDC violations or negative health reports, look elsewhere.

The consumer should ask the manufacturer of the product to explain the metabolic pathway or methodology by which his product stimulates the production of NO or provides NO to the body. The product should also be low glycemic, as insulin-stimulation is contraindicated in an arginine formula.


L-arginine derived nitric oxide (ADNO) formulas have the potential to replace Viagra for those persons choosing natural, rather than drug methodologies, and to contribute to maximum sexual performance.